“Rubber” protein, or what is elastin?

Collagen and elastin are two well-known proteins that form the basis
young skin. They are like two inseparable friends, walking hand about
hand on life, have approximately the same functions and goals. If a
about collagen they say and write a lot, then elastin is always on the second
cast Today we want to correct this injustice, and
tell about the unique properties of elastin that contribute
youth and beauty of our skin.

Content

  • What is elastin?
  • Elastin properties
  • Disintegration and synthesis of elastin. Why is this happening?
  • How to restore elastin in the skin?

What is elastin?

Elastin is a structural protein of elastic fibers that
a large amount found in connective tissue. He is present in
skin, in the walls of blood vessels, in the ligaments and lungs. Fibers
elastin have a very important quality: they are able
stretch several times over the original length.
This preserves the high strength of the fibers and their ability
return to the original state after removing the load.

elastin


These properties of elastin are determined by the glycoprotein complex protein. TO
elastin molecules have the form of twisted spirals, which
able to both curl and curl limitless
number of times All movements of facial muscles are exactly
elastin, and collagen provides the skin with density and elasticity.

So, after each movement of the muscles, facial expression of the face returns to its
the initial state. The elastin molecule is very close in structure to
collagen, but there are some significant differences in amino acid
sequences.

Elastin properties

In addition to its basic properties, elastin has
ability to absorb moisture, which provides tissues
long mode of moistening. As part of cosmetics
elastin is used primarily to restore elasticity
tissues and their moisture.

Like collagen, elastin undergoes a chemical process –
hydrolysis. In cosmetics, elastin is used only in
as hydrolyzate. When buying a cosmetic, look for
package inscription: collagen hydrolyzate, elastin hydrolyzate.
It makes no sense to buy a cream, which includes
simple elastin and collagen.

Hydrolysis is the splitting of a complex substance with the help of water. AT
the process of hydrolysis is the destruction of protein into amino acids for
its best assimilation. High molecular weight elastin is not
helps to improve skin characteristics, for this reason
elastin is hydrolyzed. When applying cream with elastin on
a peptide film is formed on the skin that moisturizes the skin and
prevents moisture loss, thus providing a delicate
lifting.

A powerful moisturizer in a cream is not at all water, as
It seems to many, and the peptides of the hydrolyzed elastin, creating on
skin peptide film.

The peptide film acts on the skin as a compress, which
keeps moisture inside tissues, not giving it out.


Here the question arises: why exactly is elastin so
powerful humidifier? Is not a good humidifier the same
collagen or hyaluronic acid, about miraculous properties
which we know well? And the thing is that the composition of elastin
non-polar amino acids are included. They are contained in the elastin molecule
up to 90%. Non-polar amino acids are located inside the protein particles and
does not interact with water, minimizing contact with it. So
Thus, they do not lose water, but completely preserve it.
Non-polar amino acids are also called hydrophobic.
amino acids.

Elastin is very effective along with collagen. These two squirrels in
harmonious tandem complement each other, increasing the effect of each
friend in cosmetic. Especially effective cosmetic
products with elastin for adult skin. The presence of elastin in them
nourishes, moisturizes and protects the skin from damage. Summarizing,
we can say that elastin is worthy of the proud name of “protein
youth, “if only because it perfectly demonstrates its
moisturizing capabilities, which we wrote about above.

Disintegration and synthesis of elastin. Why is this happening?

Like collagen, elastin decreases with age over the years.
the body. Why is this happening? The reasons are the same:

  • UV radiation;
  • action of elastase;
  • bad habits: smoking;
  • deficiency of copper and vitamin B6 in the body.

The amount of elastin in the body decreases not due to the fact that
its fibers wear out or age, and because of the adverse effects
UV irradiation. Type A UV light can penetrate very
deep into the skin. With its long-term effects on the body
decreases the synthesis of elastin and the violation of its molecular
structures. That is, in addition to reducing the production of elastin,
the molecule is undergoing major changes.

In the elastin molecule is an amino acid – desmosine. Desmosine
provides protein crosslinking, forming strong bridges between peptide
elastin links. When reducing the production of desmosine transverse
crosslinks are formed in small quantities or not formed at all. AT
as a result, elastic tissues lose strength, become thinner,
become lethargic, that is, they lose their unique properties. it
affects both the work of the organism as a whole and the state
skin.


Also under the influence of ultraviolet activates the enzyme –
elastase. In the body, the process of synthesis and degradation of elastin
is in strict balance. It is UV radiation and some more
factors contribute to the imbalance of this process. Under influence
ultraviolet light not only decreases collagen synthesis, but completely
its structure is changing, which is much worse. Since the synthesis of elastin
albeit reduced, but does not stop, and the new elastin
produced already “defective.” The result is very bad: elastin loses
ordered structure and turns into clusters of amorphous protein,
which does not contribute to youth and beauty. Skin starts
sag, becomes flabby, loses its clear relief, on it
irregularities appear, it becomes rough and dry. As a result
develops a skin disease – elastosis. Elastosis is a condition
skin that is formed due to wear and dystrophy
elastic fibers.

Chemists have long noticed that if the body lacks at least
single trace element, the whole chain of chemical can be broken
reactions. This contributes to the deterioration of certain organs and
systems, up to the terminal state (with a copper deficiency and
selenium, etc.) Insufficient intake of copper, causes
violation of elastin synthesis. In the synthesis of elastin is involved
the enzyme lysyl oxidase, which needs copper ions for its
working out.

Also in the synthesis of elastin is involved protein – decorin. It was he
regulates the formation of elastin, ensuring the formation
homogeneous, intact elastin. With its lack
low accumulation of defective elastin begins
strength.

A major role in the synthesis of elastin is also played by vitamin
AT 6. If there is a simultaneous deficiency in the body
both copper and vitamin B6, the synthesis of elastin is also
decreases.

Even children know about the dangers of smoking, but very few people know that
nicotine is bad for the skin. Nicotine stimulates the production
molecular weight metalloproteinase (MMP) molecules that
contribute to the degradation of elastin in the skin.

How to restore elastin in the skin?

To fill elastin in the cream in two ways:

  • fill its deficiency with the help of cosmetics;
  • stimulation of elastin’s own synthesis.

Immediately it is worth noting that the elastin in the cream affects only
on the top layer of the epidermis. But this is quite important. It is very
many women, however, like men, know what good means
moisturizing cream. Thanks to its moisturizing properties elastin
creates a hygroscopic film on the surface of the skin that does not
allows our skin to dry out and lose moisture. Something is being created
like a thermos: the skin is permanently moisturized, but at the same time moisture
does not evaporate from its surface.


Cosmetic creams do not affect the synthesis in any way.
elastin. Even elastin sold in ampoules improves only
surface layer of the epidermis.

To stimulate the synthesis of its own elastin is necessary
refer to procedures based on regenerative technologies.
This – plasma-lifting, placenta therapy, the use of amino acid
therapy and SPRS therapy (autologous cell based therapy).
fibroblasts).

As a result of these procedures, stimulation of one’s own
fibroblasts. Fibroblasts – connective tissue cells,
producing elastin, collagen and hyaluronic acid, which
promote skin rejuvenation.

I would like to dwell on the method based on
the use of copper-containing proteins.

We have already written above how important the microelements are, specifically copper,
for the body and skin. Lack of copper can affect
the formation of the enzyme lysyl oxidase, which in turn
promotes elastin synthesis. Increase in copper-containing elements
in the skin it promotes enhanced elastin synthesis. But should
remember that copper should be used only in protein form
(since copper in unbound form takes an active part
in the formation of free radicals that damage the elastin molecules and
collagen). Copper-containing proteins stimulate the process
skin remodeling. What is this process? Skin remodeling –
This is the process by which defective and worn out are removed.
structures (collagen, elastin), and instead they are synthesized
new ones.

While this method is not widely used and little
put into practice, but it has a large biopotential,
which has not yet been fully disclosed.

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