What is nevus Setton?

Nevus Seton – this is the usual mole around which was formed
depigmented leather rim. This pathology has another
the name is halonevus. The term is derived from the Greek word “halo” –
circle, disk, aura. The term halo also means an optical phenomenon,
when a luminous ring forms around a luminous object.
For example, a halo is often around the sun or moon.

Nevus Setton is very similar to vitiligo, but has one
characteristic feature. Vitiligo is solid depigmented
spots, and the halonevus consists of a nevus per se, which is surrounded by
depigmented rim of the rim type.

Nevus Setton is observed in people of all races, both sexes and
any age. In most cases, halonevus develops in
children and adolescents. Very often, halonevus occurs in individuals with
vitiligo and autoimmune pathologies.



  • Causes
  • Clinical picture
  • Diagnostics
  • Treatment
  • Prognosis and prevention


Modern medicine has not yet revealed the exact reasons
contributing to the development of this pathology. However well known
the fact that gallonevuses often develop in individuals with autoimmune

Some researchers believe that Nevus Setton appears
due to excessive exposure to ultraviolet radiation on the skin, since
Halonevuses often occur after sunburn.

Another part of the researchers believes that a decisive role in
the occurrence of gallonevus play autoimmune pathology, since
many patients with this type of nevus in the blood is detected
cytotoxic antibodies (proteins formed in the human body
when ingested with antigens). A depigmented beater around
nevus is a consequence of the destruction of melanocytes by cells
immune system.

Clinical picture

Nevus Setton is easy to recognize, as it has a characteristic
structure and a certain specificity. It can not be confused with
another kind of nevi. Very often, galonevus is accompanied by another
skin lesions associated with pigmentation, namely vitiligo.
Directly the node of a nevus can be of a different color and shade,
most often pink, light pink, brown,
dark brown. It is the right shape (usually round),
has clear boundaries and slightly rises above the skin. With
the occurrence of halonevus primarily forms a nevus itself, and then
depigmented bezel around it, which is three times wider
most nevus. Localized halonevus on the trunk, upper and lower
limbs. On the face, this nevus develops extremely rarely. AT
most cases nevus Setton has multiple formations
in very rare cases, single.

One should not forget the fact that halonevus refers to
melanoid nevi and has a tendency to rebirth in
malignant disease. This nevus has a long stage
development that takes years and even decades. However, this
pathology is also characterized by the fact that spontaneous
disappearance of nevus Setton. First it disappears directly by itself.
pigment node, then depigmented very slowly disappears
bezel, getting the color of healthy skin with normal color.


Diagnosis of the disease is not difficult, since
typical clinical picture and symptomatic specificity
Halonevus makes it easy to diagnose a disease.
A certain difficulty in the diagnosis appears in the case of development

For accurate diagnosis using the following methods:

  • dermatoscopy;
  • siascopy;
  • histological examination;
  • biopsy.

Dermatoscopy is a study of the skin using a special
apparatus, which increases several times the image of nevi.
This method allows you to see the slightest changes on the surface.
nevus, and also allows you to diagnose melanoma at the earliest
stages of development.

Siascopy – the most effective and accurate to date
method. The essence of the method is spectrophotometric
intracutaneous analysis of the skin in the form of a three-dimensional image. The
the method helps to effectively investigate halonevus, its structure,
color, concentration of melanin, accumulation of nevus cells and lack of
melanocytes at the depigmented site.

The most important in the diagnosis of this pathology is the exception
malignant disease, namely melanoma. The fact is that
in some cases, melanoma is very similar to nevus Setton. With
melanoma may also be observed depigmented bezel
around the pigment formation. For this reason it is necessary to hold
halonevus biopsy followed by histological examination


It is also necessary to differentiate the halonevus with the following

  • blue nevus;
  • neurofibroma;
  • a wart;
  • vitiligo.

If it is not possible to differentiate halonevus from melanoma, conduct
surgical excision of a mole with the capture of depigmented
the area and parts of healthy skin, with its subsequent histological
research. In place of the birthmark remains a scar, since
surgical excision of a mole requires suture overlap.


This pathology does not need treatment. In order not to
to aggravate the development of the disease it is necessary to protect the halonevus from
exposure to ultraviolet radiation. In the summer before
the exit to the street should be applied to the area where it is located
halonevus, a thicker layer of sunscreen. Persons with this
pathology must be in the sun at a safe time: until 11-00
o’clock in the morning and in the evening after 17-00.

It is also recommended to wear light clothing of light colors with
long sleeves that cover nevi from straight
hitting ultraviolet. Surgical excision is recommended in
case of permanent traumatization of the halonevus.

Prognosis and prevention

The prognosis is favorable. Sometimes there is a spontaneous
self healing Specific prophylaxis in this pathology is not
exists, since the reasons contributing to it are not clear
development. It is necessary to protect the skin from ultraviolet radiation with
using sunscreen with an SPF of at least 50. The sun’s rays
I can provoke a burn of the depigmented part of the halonevus, so
as this skin area does not form melanin pigment.

It is also important to avoid stress and psycho-emotional states,
which are able to initiate the development of an autoimmune state.

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